Publications

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Papers

Aromatase | Breast Cancer | Computational Biology

Mallur, Dhrithi Jayasimha, B. Lavanya, Sheshadri S. Temkar, V. Arun, and Benedict C. Paul. "Exploring okra-derived compounds as prospective aromatase inhibitors: a computational study for enhanced breast cancer therapy." Journal of Biomolecular Structure and Dynamics (2024): 1-9.
Temkar, Sheshadri S., Amruta Sridhara, Dhrithi Jayasimha Mallur, Deepak Ishwara Shivaprakash, Divya Iyengar, Nritam Das, and Benedict Paul C. 2024. “Potential Aromatase Inhibitors from Centella Asiatica with Non-Synonymous SNPS - A Computational Approach.” Current Computer-Aided Drug Design 20 (4): 341–58. doi: 10.2174/1573409919666230525151933. PMID: 37231718
Paul, C. Benedict, and C. Sudandiradoss. "Functional and structural characterization of deleterious nsSNPs of Cyp19a1 based on binding affinity and stability-A computational approach." Gene Reports 5 (2016): 34-39.
BENEDICT, PAUL C., and C. SUDANDIRADOSS. AROMATASE INHIBITORS-TYPES AND ADVANTAGES International Journal of Pharmacy and Pharmaceutical Sciences, 8 (8) (2016), 1–7.

Enterococcus faecalis | Dental Pathogens | PCR

Dhanushiya R, Abinaya S, Siva V, Paul CB. Investigating the presence and virulence potential of Enterococcus faecalis, with a focus on the hyaluronidase factor, in environmental samples: Insights from a pilot study. Sri Ramachandra J Health Sci. doi: 10.25259/SRJHS_55_2023
Lokitha R. , Nandakumar Namitha, Harish K. , Arulmozhi P. , Jayakumar Aarthi, Anbarasi K. and Benedict Paul C.*, Antimicrobial Therapeutic Strategies for Enterococcus faecalis In Dental Infections - Past, Present and Future, Anti-Infective Agents 2023; 21(3) : e200123212930
M. Prasanth, Meera Raju, S. Divakar, S. Abirami, H. Hajarah, K. Uma Harini, S. Senthilnathan, Benedict Paul C. (2016). Detection of gelE and factors affecting gelatinase activity of enterococcus faecalis isolates. Asian Jr. of Microbiol. Biotech. Env. Sc., 18(1), 257–261.
Manohar, Prasanth, Gowtham Kumar G, Hajarah Hussain, and Benedict Paul C. (2016). “Distribution of virulence factors among vancomycin resistant enterococcus faecalis from dental isolates.” Asian Journal of Pharmaceutical and Clinical Research 9 (3): 103–5.

Collaboration

Goutham PAJ, Kalaiselvam R, Ganesh A, Benedict Paul C. Antibacterial Efficacy of Irrigants with Varying Osmolarity on E. faecalis Biofilm: An In Vitro Study. J Contemp Dent Pract. 2022 Oct 1;23(10):998-1003. doi: 10.5005/jp-journals-10024-3417. PMID: 37073912.
Appapalam, Selvakumar Thanganadar, Benedict Paul, Sumathy Arockiasamy, and Rajasekar Panchamoorthy. "Phytofabricated silver nanoparticles: Discovery of antibacterial targets against diabetic foot ulcer derived resistant bacterial isolates." Materials Science and Engineering: C (2020): 111256. (Impact Factor 5.88)
Hemalatha, C. R., P. A. Abhinand, Maithreyi Iyer, Benedict C. Paul, Anupma Jyoti Kindo, Thyagarajan Ravinder, and P. Dhanapalan. "Phytochemical derivatives targeting fliJ flagellar protein from Escherichia coli." Bioinformation 14, no. 9 (2018): 465-470.
Rosaline H, Kandaswamy Deivanayagam J, Paul B. Depth of penetration and biovolume of enterococcus faecalis and fusobacterium nucleatum biofilm into dentinal tubules using confocal microscope and co-aggregation assay. ejpmr, 2018,5(5), 270-274.
Markandeyan, D., Kannaiyan, S., Suresh, S., Nimmakayala, R., Ilamurugan, R., Santhalingam, K., & Benedict Paul C. (2016). Virtual screening of phytochemicals for methotrexate like dihydrofolate reductase and aminoimidazole-4-carboxamide ribonucleotide (aicar) transformylase inhibitory property using molegro virtual docker. International Journal of Pharmacy and Pharmaceutical Sciences, 8(5), 83–87.
Markandeyan, D., K. Santhalingam, S. Kannaiyan, S. Suresh, and Benedict Paul C. “VIRTUAL SCREENING OF PHYTOCHEMICALS OF MORINDA CITRIFOLIA AS ANTI-INFLAMMATORY AND ANTI-ALZHEIMER AGENTS USING MOLEGRO VIRTUAL DOCKER ON p38-Î± MITOGEN ACTIVATED PROTEIN KINASE ENZYME”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 8, no. 6, Nov. 2015, pp. 141-5

Masters Dissertation

Padmesh, P., Reji, J. V., Benedict Paul, C., Mukunthakumar, S., Praveen, G., & Seeni, S. (2009). Analysis of genetic variability in two diploid Musa cultivars using RAPD. Biologia Plantarum, 53(4), 711–714. doi:10.1007/s10535-009-0128-6.

Posters (International)

Posters were selected by the Selection Committee to be presented at the 1st TCGA conference and workshop in India - Multi-Omics studies in cancer at the Indian Institute of Science, Education and Research (IISER), Pune between 18th and 23rd of September 2019.

aidb.in - a functional database for Aromatase Inhibitors (AIs) - See Poster
Identification of potent anti-metastatic compounds for tubulin with G13R, A100T, N329H in Breast Cancer - a computational approach - See Poster

Poster/Oral Presentations (National)

(Selected few)

Karishma K, Shafeen Tabassum, Ramya Lakshmi D, Benedict Paul C (2022). Single Nucleotide Polymorphism, S100Y may not impede aromatase inhibition activity of Pomegranate - a computational study. Presented at the National Seminar on Nutraceuticals: A Novel Approach to Health Sri Ramachandra Institute of Higher Education and Research (Deemed to be Universit y), Porur, Chennai - 600116. View Poster (Won Second Prize)
Rabeka M, Sangeetha D, Nandhini V, Benedict Paul C (2018). Identification of potent antimicrobial agent for the dental pathogen, Enterococcus faecalis. Presented at SRM Institute of Science and Technology, Chennai. View Poster
Arulmozhi P, Surya Lakshmi A R, Benedict Paul C (2017). Molecular detection of the virulence gene, cob of Enterococcus faecalis from dental isolates. Presented at Dr. M.G.R. Educational and Research Institute, Chennai. View Poster
Poorvaja T I, Ezhilvannan A, Janet Bertilla X, Sreewardhini S, Benedict Paul C. (2016). Incidence of the sex pheromone genes cpd, ccf and cad of Enterococcus faecalis from dental isolates. Presented at Dr. M.G.R. Educational and Research Institute, Chennai. View Poster
Hajarah, H., Gowtham, Kumar G., Benedict Paul, C. (2015). Molecular detection of the virulence gene, enlA (enterolysin A) of Enterococcus faecalis from dental isolates. Presented at Stella Maris College, Chennai. View Presentation
Divakar S, Janavi S, Prasanth M, Anbarasi K, Benedict Paul, C. (2014). Collagen Binding Protein gene, ace may contribute to the virulence of Enterococcus faecalis from dental isolates. Presented at In Viverra 2014. Bannari Amman Institute of Technology, Sathyamangalam.

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